Translational Research Related Content

Staff Profile: Ole Isacson, Dr Med Sci

Dr. Ole Isacson is a professor of neurology at Harvard Medical School and founding director of the Neuroregeneration Research Institute at McLean Hospital. His work is focused on the understanding and treatments of neurodegenerative disease, with particular emphasis on distinguishing critical...

Staff Profile: Brian P. Brennan, MD, MMSc

Brian P. Brennan, MD, MMSc, is an associate professor of psychiatry at Harvard Medical School and is the medical director of the Obsessive Compulsive Disorder Institute at McLean Hospital—an intensive residential treatment facility for patients with severe OCD and related disorders. He is also the...

Staff Profile: Courtney Beard, PhD

Courtney Beard, PhD, is an associate professor of psychology in the Department of Psychiatry at Harvard Medical School and director of the Cognition and Affect Research and Education (CARE) Laboratory at McLean Hospital. Dr. Beard’s research aims to delineate cognitive and affective mechanisms...

Staff Profile: Marc J. Kaufman, PhD

Dr. Kaufman is director of McLean Hospital’s Translational Imaging Laboratory, associate professor of psychiatry at Harvard Medical School, co-director of the NIDA T32 post-doctoral training program at McLean, and a Partners Human Research Committee member. He conducts translational research in...

Clinical Research at McLean

Through scientific investigations on human participants, clinical researchers try to find better ways to diagnose, prevent, and treat mental health disorders. The human brain is a marvelous—and marvelously complex organ. It has long been known that our brain is what sets us apart from other species...

Staff Profile: Jenna M. Traynor, PhD

Jenna M. Traynor, PhD, is a clinical psychologist and clinician-scientist. She conducts research within McLean’s Division of Women’s Mental Health. Her research and clinical practice focus on treatment for borderline personality disorder (BPD), trauma-related disorders (e.g., post-traumatic stress...

Staff Profile: Robyn A. Ellis, PhD

Robyn A. Ellis, PhD, is a post-doctoral research fellow under the mentorship of R. Kathryn McHugh, PhD, in the Stress, Anxiety, and Substance Use Laboratory. Dr. Ellis’ graduate research focused on examining emotional mechanisms of post-traumatic stress symptoms and risk-taking behaviors. In 2022...

Staff Profile: Benjamin C. Silverman, MD

Benjamin C. Silverman, MD, is the senior IRB chair at Mass General Brigham. He is additionally director of ethics for the McLean Institute for Technology in Psychiatry, chair of the Mass General Brigham Embryonic Stem Cell Research Oversight (ESCRO) Committee, and at Harvard Medical School, he...

Staff Profile: Alessandro S. De Nadai, PhD

Alessandro S. De Nadai, PhD, is a translational data scientist who focuses on improving pediatric mental health outcomes. He and his team take new findings in computer science, mathematics, and statistics and translate them into clinically actionable information. He has applied new developments in...

Staff Profile: Manuel Kuhn, PhD

Manuel Kuhn, PhD, is a post-doctoral research fellow in the Laboratory for Translational and Affective Neuroscience, directed by Diego A. Pizzagalli, PhD. Dr. Kuhn completed his doctoral degree at the University Medical Center Hamburg-Eppendorf, Germany, where he examined the neurobiological...

Staff Profile: Allen J. Bailey, PhD

Allen J. Bailey, PhD, is a clinical investigator in the Division of Alcohol, Drugs, and Addiction at McLean Hospital. His research aims to understand heterogeneity among individuals with substance use disorders (SUD) and to improve treatment outcomes in SUD populations. He is particularly interested...

Staff Profile: Victoria R. Votaw, PhD

Victoria R. Votaw, PhD, is a clinician-scientist in the Division of Alcohol, Drugs, and Addiction at McLean Hospital. Her research focuses on improving treatment outcomes for substance use and co-occurring disorders using precision medicine approaches. Her recent projects have aimed to validate core...

Staff Profile: Beier Yao, PhD

Beier Yao, PhD, is a clinician-scientist in the Division of Psychotic Disorders. She has expertise in neuroimaging, electrophysiology, eye tracking, and psychophysics, with a background in clinical psychology, neuroscience, and statistical modeling. Dr. Yao uses a multimodal approach to study the...

Clinical Trials and Research Studies

Mental health research is conducted to study the human brain and learn about psychiatric illnesses with the goal of finding causes and improving treatment. Volunteers in clinical studies help researchers contribute to advances in psychiatric research. To learn more about current McLean Hospital...

LEAP Center™

The goal of the Laboratory for Early Psychosis (LEAP) Center is to develop collaborations, data systems, and methods to better understand the unique characteristics in first episode psychosis patient outcomes and treatment impacts. The LEAP Center TM is one of the National Institute of Mental Health...

Staff Profile: Frank I. Tarazi, MBBS, PhD, EMBA

Frank I. Tarazi, MBBS, PhD, EMBA, is a preclinical and clinical expert in the diagnosis and treatment of Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease, schizophrenia, bipolar disorder, depression, and ADHD. He has published over 140 articles and reviews in highly cited...

Staff Profile: Alexandra L. Silverman, PhD

Alexandra L. Silverman, PhD, is a clinician scientist in the Cognition and Affect Research and Education (CARE) Laboratory at McLean Hospital. Her research focuses on developing, evaluating, and implementing digital mental health interventions for anxiety and depression in clinical practice settings...

Staff Profile: Joshua C. Brown, MD, PhD

Joshua C. Brown, MD, PhD, is a psychiatrist, neurologist, and neuroscientist. He is medical director of the Transcranial Magnetic Stimulation (TMS) Service and director of TMS research in the Division of Depression and Anxiety Disorders at McLean Hospital. Dr. Brown is also director of the Brain...

Staff Profile: Laura Payne, PhD

Laura Payne, PhD, is the director of the Clinical and Translational Pain Research Laboratory at McLean Hospital. Her research focuses on identifying neurobiological, behavioral, and psychological biomarkers related to pain, particularly menstrual pain in adolescents. Specifically, she is interested...