The vast majority of those who struggle with clinical depression—also known as major depressive disorder (MDD)—are able to find relief through some combination of medication and traditional forms of therapy. However, for roughly 30% of those with MDD, antidepressants prove to be largely ineffective, and their depression is deemed to be treatment resistant.
So what is treatment-resistant depression (TRD), and how do you determine when a patient is a candidate for therapeutic approaches such as transcranial magnetic stimulation (TMS)? If TMS isn’t the best next step, what other options are out there?
Join us as Joshua C. Brown, MD, PhD, shares what makes some forms of depression especially difficult to treat, explores proven, cutting-edge treatment, and answers questions about lifestyle changes for helping manage TRD.
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Joshua C. Brown, MD, PhD, is a psychiatrist and neurologist. He is medical director of the Transcranial Magnetic Stimulation (TMS) Service and director of TMS research in the Division of Depression and Anxiety Disorders at McLean Hospital. Dr. Brown is also director of the Brain Stimulation Mechanisms Laboratory at McLean.
Dr. Brown is working to advance TMS through service on the Clinical TMS Society’s board of directors, as a member-at-large and research committee co-chair. His research uses neurophysiology to measure TMS effects in combination with relevant receptor-modulation drugs in human subjects.
