Content Related to PTSD / Trauma

Groundbreaking PTSD Study by McLean Researchers Among NIH Director’s Top Science Highlights of 2024

In a landmark recognition, a study led by Nikolaos P. Daskalakis, MD, PhD, and Kerry J. Ressler, MD, PhD, of McLean Hospital was recently featured in the National Institutes of Health (NIH) Director’s Top Science Highlights of 2024. The study, which delves into the biological underpinnings of post...

Shedding Light on Dissociative Identity Disorder: A Global Conference Breaks Barriers

Last September, mental health professionals from around the world gathered virtually for a groundbreaking event: Stronger Together: Dissociative Identity Disorder Past, Present, and Future. Hosted by McLean Hospital and Harvard Medical School Continuing Education, the conference offered a deep dive...

New Insights Into Trauma-Related Intrusive Memories in PTSD

Trauma-related intrusive memories (TR-IMs)—memories related to a traumatic event that come to mind spontaneously—are central symptoms of post-traumatic stress disorder (PTSD) and may be critical treatment targets for PTSD. Their frequency and intensity are usually measured with retrospective reports...

Research Spotlight: Impact of Neighborhood Resources on Resilience After Trauma

E. Kate Webb, PhD, a research fellow at McLean Hospital, led an investigation into whether individual resources and neighborhood resources, like green space, might impact neurobiology and the trajectory of post-traumatic stress disorder (PTSD) symptoms. Her research was published July 31 in JAMA...

Honorary Trustee Establishes Fund To Support Hill Center Staff

It started with a phone call. Jeanne Blake, a McLean Hospital honorary trustee, had provided philanthropic support to the Trauma Continuum of Care at the Hill Center. Now, she heard that hospital staff—still weary from the demands of the pandemic—could use a boost. So, she called Milissa Kaufman, MD...

Researchers Unveil Shared and Unique Brain Molecular Dysregulations in PTSD and Depression

A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member of the Mass General Brigham health care system, working with colleagues at The...

Joining Forces To Provide a Full Continuum of Trauma-Focused Care

McLean Hospital has a strong reputation as being one of the premier locations in the United States for trauma-related patient care and research. With exposure to traumatic events occurring worldwide, we continue to adapt to meet the needs of the communities we serve. To address this, McLean’s Hill...

Understanding Gender Differences in Mental Health Conditions

Late in her medical residency, Amanda Sedgewick, DO, was running treatment groups for women with substance use disorders. Patients would disappear from treatment for weeks at a time and Sedgewick realized they were in abusive relationships—which was keeping them away from the clinic. So, she began...

Trauma-Informed Training Workshops Prompt Meaningful Changes, According to Outcomes Surveys

A study of 598 people across various industries who underwent a two-day training workshop where they learned about trauma-informed care and how to deploy these skills within their organizations, found participants reported significant gains in knowledge of trauma and made improvements to...

Single-Cell Study Reveals Genes That May Be Involved in Post-Traumatic Stress and Major Depressive Disorders

An international team led by investigators at McLean Hospital analyzed the genes expressed in approximately 575,000 individual cells from the brains of people with and without post-traumatic stress and major depressive disorders (PTSD and MDD), revealing new insights into the mechanisms behind the...

McLean Hospital Supports Effort to Establish Trauma-Informed Care Training Institute in Angola

When she was in the fourth grade, Alisha Moreland-Capuia, MD, and her classmates were asked by their teacher what they wanted to do when they grew up. Moreland-Capuia had one resounding desire in her mind that would ultimately shape her life’s work: She wanted to help people who were suffering...

Investigators Shed New Light on Brain Activity Related to Dissociative Symptoms

Trauma can cause dissociative symptoms—such as having an out-of-body experience, or feeling emotionally numb—that may help an individual cope in the short term but can have negative impacts if the symptoms persist for a long period of time. In a new study recently published in...

McLean Hospital Launches Free Course Focused on Global Impacts of Trauma

Psychological trauma knows no boundaries: it affects people of every background, ethnicity, socioeconomic status, age, and gender. The impact on people around the globe is significant. According to a 2016 study, over 70% of those surveyed across six continents have experienced a traumatic event...

Feelings of Detachment Predict Worse Mental Health Outcomes After Trauma

Results from the largest prospective study of its kind indicate that for individuals who experience trauma, the presence of dissociation—a profound feeling of detachment from one’s sense of self or surroundings—may indicate a high risk of later developing severe post-traumatic stress, depression...

Video: Lecture – Examining the Connections of PTSD and Cardiovascular Disease

Presented by Antonia V. Seligowski, PhD, McLean Hospital – McLean Forum lecture Post-traumatic stress disorder (PTSD) is associated with a greater risk of cardiovascular disease as compared to the general population. Individuals with PTSD are more likely to have myocardial infarction, stroke, and...

Investigators at McLean Receive Award To Test Xenon Gas as Treatment for Opioid Use Disorder

Researchers at McLean Hospital, in collaboration with Nobilis Therapeutics, have been awarded a grant to test a novel xenon gas-based treatment for opioid use disorder. Highlights McLean Hospital researchers have been awarded a grant by the National Institute on Drug Abuse to test xenon gas to...

Dr. Alisha Moreland-Capuia Leads McLean’s New Culturally Informed Trauma Care Program

Psychiatrist Alisha Moreland-Capuia, MD, has been recruited to lead McLean Hospital’s new Program for Culturally and Trauma-Informed Community Outreach. Moreland-Capuia, an expert in trauma-informed care, specializes in working with underserved populations. She moved from Oregon Health & Science...

McLean Launches Institute for Trauma-Informed Systems Change

On Tuesday, July 6, health care leaders, government officials, and journalists from across the U.S., Europe, and Africa joined Alisha Moreland-Capuia, MD, for a virtual meet and greet to launch McLean Hospital’s new Institute for Trauma-Informed Systems Change. Moreland-Capuia, the institute’s...

McLean Hospital Joins Partnership to Research Generational Trauma

McLean Hospital has partnered with the nonprofit arm of The Connor Group, a real estate investment firm, as well as the University of Dayton and Dayton Children’s Hospital, on a groundbreaking research project aimed at understanding the biological link between childhood hardships and mental...

New Study Uncovers Details Behind the Body’s Response to Stress

The biological mechanisms behind stress-related psychiatric conditions, including major depressive disorder and post-traumatic stress disorder (PTSD), are poorly understood. New research now details the interplay between proteins involved in controlling the body’s stress response and points to...

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