Content Related to Nikolaos Daskalakis

Groundbreaking PTSD Study by McLean Researchers Among NIH Director’s Top Science Highlights of 2024

In a landmark recognition, a study led by Nikolaos P. Daskalakis, MD, PhD, and Kerry J. Ressler, MD, PhD, of McLean Hospital was recently featured in the National Institutes of Health (NIH) Director’s Top Science Highlights of 2024. The study, which delves into the biological underpinnings of post...

Researchers Unveil Shared and Unique Brain Molecular Dysregulations in PTSD and Depression

A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member of the Mass General Brigham health care system, working with colleagues at The...

Single-Cell Study Reveals Genes That May Be Involved in Post-Traumatic Stress and Major Depressive Disorders

An international team led by investigators at McLean Hospital analyzed the genes expressed in approximately 575,000 individual cells from the brains of people with and without post-traumatic stress and major depressive disorders (PTSD and MDD), revealing new insights into the mechanisms behind the...

McLean Researcher Nikolaos Daskalakis Awarded International Life Science Grant

Nikolaos P. Daskalakis, MD, PhD, director of the Neurogenomics and Translational Bioinformatics Laboratory at McLean Hospital, is part of an international research collaboration that has been awarded a $1.14 million grant from the prestigious Human Frontier Science Program (HFSP). Highlights An...

Neuron-Based Gene Expression Study Reveals Insights on Fear and Its Regulation

Fear and fear extinction learning (the gradual reduction of fear by repeated exposure to the feared object) are adaptive processes caused by molecular changes in specific brain circuits, and they’re perturbed in conditions such as anxiety and post-traumatic stress disorder. A new study by...

Expression of Certain Genes May Affect Vulnerability to Post-Traumatic Stress Disorder

Results from a new study suggest that whether certain genes are expressed—turned on or off—may play a role in susceptibility to post-traumatic stress disorder (PTSD). The study, which was conducted by an international team led by investigators at McLean Hospital and appears in the journal Cell...

Launching Careers With Coveted K Awards

K awards, which are part of the National Institutes of Health (NIH) Research Career Development Awards, support the next generation of scientists focused on addressing the country’s most pressing biomedical challenges. These awards serve to provide both salary and research for intensive, focused...

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